{"product_id":"doctors-best-sam-e-400-mg-vegan-gluten-free-soy-free-mood-and-joint-support-60-enteric-coated-tablets","title":"Doctor's Best SAM-e 400 mg, Vegan, Gluten Free, Soy Free, Mood and Joint Support, 60 Enteric Coated Tablets","description":"\u003cdiv\u003e\u003cdiv id=\"productDescription\" class=\"a-section a-spacing-small\"\u003e\n \u003cp\u003e\u003cspan\u003eSAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none. S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones. The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market. SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.* SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.* SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.*\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003cdiv\u003e\u003cdiv id=\"feature-bullets\" class=\"a-section a-spacing-medium a-spacing-top-small\"\u003e\n \u003ch2 class=\"a-size-base-plus a-text-bold\"\u003eAbout this item\u003c\/h2\u003e\n \u003cdiv data-a-expander-collapsed-height=\"300\" class=\"a-expander-collapsed-height a-row a-expander-container a-expander-partial-collapse-container\"\u003e\n  \u003cdiv data-expanded=\"false\" class=\"a-expander-content a-expander-partial-collapse-content\"\u003e\n   \u003cul class=\"a-unordered-list a-vertical a-spacing-mini\"\u003e\n    \u003cli class=\"a-spacing-mini\"\u003e\u003cspan class=\"a-list-item\"\u003e Doctor's Best SAMe Double Strength is proven to enhance mood and promote cognitive health \u003c\/span\u003e\u003c\/li\u003e\n    \u003cli class=\"a-spacing-mini\"\u003e\u003cspan class=\"a-list-item\"\u003e SAMe is essential for the healthy metabolism of the major brain transmitters dopamine, serotonin and norepinephrine \u003c\/span\u003e\u003c\/li\u003e\n    \u003cli class=\"a-spacing-mini\"\u003e\u003cspan class=\"a-list-item\"\u003e SAMe has been proven to promote joint comfort and mobility and supports liver health and detoxification \u003c\/span\u003e\u003c\/li\u003e\n    \u003cli class=\"a-spacing-mini\"\u003e\u003cspan class=\"a-list-item\"\u003e SAMe's effectiveness has been proven with 18 controlled human trials published over 40 years \u003c\/span\u003e\u003c\/li\u003e\n    \u003cli class=\"a-spacing-mini\"\u003e\u003cspan class=\"a-list-item\"\u003e Pharmaceutical grade, Non-GMO, Gluten Free, Vegan \u003c\/span\u003e\u003c\/li\u003e\n   \u003c\/ul\u003e\n   \u003c!-- Loading EDP related metadata --\u003e\n  \u003c\/div\u003e\n \u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003cdiv\u003e\u003cdiv class=\"a-section content\"\u003e\n \u003ch4\u003eIngredients\u003c\/h4\u003e\n \u003cp\u003e\u003c\/p\u003e\n \u003cp\u003eSAM-e (S-Adenosyl-L-Methionine disulfate p-toluensulfonate) 400 mg. Other Ingredients: Microcrystalline cellulose, magnesium silicate, stearic acid, magnesium stearate (vegetable source), flake shellac dewaxed, magnesium hydroxide, glycerol, silica, arginine base, sodium alginate, calcium oxide\u003c\/p\u003e\n \u003cp\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e","brand":"HappyTots","offers":[{"title":"Unflavored \/ 30 Count (Pack of 1)","offer_id":48680053211385,"sku":"B0011FTJZ0","price":123.0,"currency_code":"CAD","in_stock":true},{"title":"Unflavored \/ 60 Count (Pack of 1)","offer_id":48680053244153,"sku":"B004YLAXOE","price":128.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/4836\/5561\/files\/717Si9dY1oL.jpg?v=1784448103","url":"https:\/\/primebio.ca\/products\/doctors-best-sam-e-400-mg-vegan-gluten-free-soy-free-mood-and-joint-support-60-enteric-coated-tablets","provider":"PrimeBioHealth","version":"1.0","type":"link"}